Over the centuries, infectious diseases caused by viruses have seriously threatened human health globally. Currently, COVID-19 - the causative pathogen of Coronavirus Disease, has rapidly spread across China and around the world, causing an outbreak of acute infectious pneumonia. So far no specific anti-virus drugs or vaccines are available for the treatment of this sudden and lethal disease, there is an urgent need to find an alternative solution to prevent and control the replication and spread of the virus. Spirulina is a microscopic edible blue- green vegetable algae and it is consider as one of the richest source of protein, all amino acids, organic vitamins and Bio-chelated minerals required for human body. Besides nutrition, it is loaded with unique phytonutrients like antioxidant phycocyanin, polysaccharides and sulfolipids that prevent inflammation enhance the immune system, possibly reducing risks of infection and cancer. It is indicated as a safe food supplement, and the World Health Organization has supported it as a health nutrient. Here we have summarized the available information concerning the immune boosting and antiviral activity of spirulina based on clinical trial using PubMed and Web of Science. The results of the searching greatly support that Spirulina presents both immune boosting and antiviral effects. Calcium Spirulan(Ca-SP)- a natural sulfated polysaccharide and Cyanovirin-N (CV-N) - Carbohydrate-binding agent (CBAs) isolated from spirulina are potent antiviral agents. Many clinical and Pre-clinical research reported that both exhibited antiviral activity of against many viruses such as hepatitis, HIV, influenza, herpes virus Herpes simplex virus type 1, human cytomegalovirus, measles virus and mumps virus. Based on this review, spirulina could be considered as therapeutics antiviral agent for coronavirus.
Spirulina plantensis, Immune Booster, Anti-inflammatory, Antioxidant, Antiviral
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