The coronavirus disease 19 (COVID-19) is a highly transmittable and pathogenic viral infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which emerged in Wuhan, China and spread around the world. Genomic analysis revealed that SARS-CoV-2 is phylogenetically related to severe acute respiratory syndrome-like (SARS-like) bat viruses, therefore bats could be the possible primary reservoir. The intermediate source of origin and transfer to humans is not known, however, the rapid human to human transfer has been confirmed widely. In this document we will analyze the structure and diversity of the pathogen and we will also discuss the previous emergence of human coronaviruses like Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and Middle East Respiratory Syndrome (MERS-CoV).
Coronavirus, SARS-CoV-2/COVID-19, Origin, Outbreak, Spread, Natural Analysis: Protein homology modelling Molecular Docking and Molecular dynamics simulation
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