Bioanalytical methods are widely used to quantitate drugs and their metabolites in plasma matrices and this method are applied to study in the areas of human clinical and nonhuman study. Bioanalytical methods employed for the quantitative estimation of drugs and their metabolites plays an important role in estimation and interpretation of bioequivalence, pharmacokinetic, and toxicokinetic studies. The major bioanalytical role is method development, method validation, and sample analysis. Techniques such as high-pressure liquid chromatography (HPLC) and liquid chromatography coupled with double mass-spectrometry (LCMS-MS) can be used for bioanalytical studies.
Method development, Analyte, Validation of bioanalysis techniques, Validation parameter
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