Phytoconstituents present in the ethanolic extract of Combretum hispidum leaves were explored by Gas Chromatography-Mass Spectrometry analysis. The compounds were identified by the gas chromatography coupled with the mass spectrometry. The molecular weight and structure of the compounds of Combretum hispidum leaves were ascertained by interpretation of the spectrum of GC-MS using the database of National Institute of Standard and Technology (NIST). GC-MS analysis of Combretum hispidum leaves revealed the presence of nineteen biological active compounds. The compounds are N-Tosyl-dl-3,4-dehydroprolylglycine, ethyl ester, 1-n-Butoxy-2,2,3,3-tetramethylaziridine, 2-Butenoic acid, 3-methyl-4-[tetrahydro-3,4-dihydroxy-5-[[3-(2-hydroxy-1-methylpropyl)oxiranyl] methyl]-2H-pyran-, Cobalt, octacarbonyl(zinc)di-, (2Co-Zn), 6''-Dehydroxy-2'',3',3'',4',4'',5,7-hepta-O-methylisoorientin, 2-naphthalenol, 3-[5-(3-nitrophenyl)-1,3,4-oxadiazol-2-yl]-, L-Proline, N-(1-naphthoyl)-, dodecyl ester, 3,6-Dispirocyclohexyl-1,2,3,4,5,6,7,8-octahydro-1,8-acridinedione, Sarcosine, N-(2-chloroethoxycarbonyl)-, heptadecyl ester, Cycloocta[1,2-b:4,3-b':5,6-b'':8,7-b''']tetrakis[1]benzothiophene, Butanoic acid, 2-chloro-3-methyl-, 4-(5-heptyl-2-pyrimidinyl)phenyl ester, Friedooleanan-1-one, 3,24-dihydroxy-, 9-O-Methyl-4,5-deoxymaytansino, Ditelluride, di-1-naphthalenyl, tert-Butylstibinous acid thioanhydride, l-Leucine, N-methyl-n-pentadecafluorocarbonyl-, octadecyl ester, 2,5-Dichloro-N-ethyl-N-phenyl-benzamide, 2-Thiophenylacetic acid, 2,2,2-trifluoroethyl ester, Methyl 8-[5-(methoxycarbonyl)methyl-2-furyl]octanoate. It was concluded that the bioactive compounds support the use of C. hispidum leaves in the treatment of diseases like cancer, anaphylactic shock, renal failure, diabetes and hypertension.
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