Empirical antimicrobial therapy for urinary tract Escherichia coli infections in the Bamenda community and its environs where the Bamenda Regional Hospital is located, is of major importance since it has helped to obtain medications of choice, deduce appropriate prescriptions and a standard antibiotic profile for Escherichia coli in isolates from urine cultures obtained from patients. This study was a prospective and analytical study on patients who consulted in the Bamenda Regional Hospital with one or more signs and symptoms of urinary tract infections. Adopting an open ended quantitative approach, we aimed at determining antimicrobial susceptibility profile for Escherichia coli from isolates of urine culture. Fifty (50) samples were considered in this study. The study precisely consisted of collection of specimens, identification and isolation of Escherichia coli strains in cultures, and conduction of in-vitro antimicrobial susceptibility testing by the Disc Diffusion Technique. A total of 75 culture respondents were isolated using the CLED agar, out of these, 50 (66.7%) were E. coli positive against 9(33.3%) other bacteria . In the antibiotic susceptibility testing, there was 81% susceptibility to Ciprofloxacine, Cefotaxime (68%), Ceftriaxone (56%), Gentamycin (24%), Penicillin (18%), Doxycycline (12%), and Erythromycin (6%), Tetracycline (0%). Anti-bacterial susceptibility showed that ciprofloxacin (81%), was highly effective and to a lesser extent to the third generation cephalosporin (Céftriaxone 56% Céfotaxime(68%). High resistance was recorded for gentamycin (31%), Amoxicilline +A. clavulanique (36%), amoxicillin (50%), penicillin (50%), tetracyclin (62%), erythromycin (68%), doxycycline(81%). Traditional medicine and drug abuse may greatly contribute to drug resistance development in this environment. This study challenges the health body as a whole to implement adequate means of epidemiological surveillance antibiotic sensitivity of bacterial strains isolated in laboratories.
Antibiogram, urine isolates, and Escherichia coli
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