Polydactyly is genetic disorder in which there is mutation of gene that is located on short arm of chromosome 7. One gene that can cause polydactyly is GLI3 and it is one among number of genes that are known to be involved in the patterning of tissues & organs during development of the embryo. Mutations of GLI3 gene during development will cause two types of polydactyly. Those are postaxial(ulnar) and preaxial(radial) polydactyly. The treatment plan is based on the outcome of analysis of patient’s medical history, social history, motivation, social and psychological disturbance.
Mutations, gene, postaxial, preaxial, polydactyly
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