Diabetes mellitus is a common chronic disorder prevalent all over the world and antioxidant therapy for diabetes patients may be helpful in relieving their symptoms and complications. In present era people of developing countries and developed countries looking towards herbal medicine for mange diabetes mellitus, due to long term acceptability and safety of herbal medicine. In Ayurveda medical system, herbal antioxidants have been widely employed for management of various disease such as diabetes mellitus, cancer and heart diseases. With this background this research project was designed to evaluate the antioxidant activity of selected decoctions which are used for management of diabetes mellitus in Ayurveda medicine. Antioxidant potential was evaluated through 2, 2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging method. The results of this study revealed that the mean value of absorbance and scavenging activity as 0.291and 59% for decoction of Lipa Kandali (LK), 0.313 and 56% for decoction of Nisha Thripal (NT), 0.292 and 58% for decoction of Kathaka Khadhira (KK), 0.422 and 40% for decoction of Thriphala Kathakan (TK) at 0.5µg/ml and 0.713 for control test. All tested antidiabetic decoctions were showed antioxidant activity. The antioxidant activity of the herbal pharmaceuticals is used to manage clinical features of diabetes mellitus as well as they are played an important role in the relief of long-term complications in diabetes mellitus by reducing the oxidative stress.
Diabetes mellitus, Antioxidant activity, Herbal decoctions
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