In the developmental milestones of Rasashastra, use of metals in combined form plays a very significant role. Today modern pharmacologists and scientists are struggling very hard to find out new safe and efficacious drugs with the help of combinatorial chemistry and co-ordination chemistry. But ancient Rasa scholars have already developed and utilized such drugs clinically with wonderful results. One such novel combinatorial molecule is” Pittala”Rasashastra has too many mineral and metallic drugs, among them Pittala is one such Mishra loha which is the combination of Tamra and Yashada in the ratio of 2:1, as it inherits property of both metals that makes it more efficacious in therapeutic action . Pittala Having tikta rasa, ruksha guna and lekhana property and it is considered as best Krimighna. Also indicated in Pandu, Kamala, Kushta Roga, and Vataroga. Bhasmeekarana is that process by which inorganic substances like metals and minerals are converted into a safe non-toxic, biocompatible and non-elemental component. As Nano the particle size, better will be the absorption rate.Maarana of Pittala with two different procedures is an attempt to focus on rationality behind exploring different procedures for maarana of Pittala.
Pittala bhasma, Gajaputa, Shodhana, Maarana, Hingula, Haratala, Gandhaka, Manashila, Method 1(HHPB), Method 2(GMPB)
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