The disease Bhagandara is included among Ashtamahagadas by Acharya Sushruta. The disease Bhagandara can be correlated to Fistula-in-ano. Incidence of Fistula in India is 17-20% in a defined population of some states. It is the recurrence nature of Fistula which makes difficult for treatment. Ksharasutra is a proven Para-surgical procedure for the management of Fistula-in-ano. A randomized clinical comparative study was conducted on 40 patients of Bhagandara and they were divided in to two equal groups. Patients of Group A were treated with Koshataki Ksharasutra and Group B were treated with Apamarga Ksharasutra. Pharmacological properties of kshara prepared out of different drugs behave differently. Therefore it is logical to hypothesis that kshara made out of Koshataki which is having Kapha-pittahara13 property may cause less incidence of burning because of its Tikta rasa. Crude extract of drug Koshataki (LuffaAcutagula) and its isolated compound possess broad antioxidants, antimicrobial, analgesic and anti-inflammatory property14. So the treatment modality will be better acceptable to the patient when compared to classical Apamarga ksharasutra. In the present study, the effect of treatment in both the groups showed statistically highly significant, and statistically Non-significant in between two groups. Overall results of treatment in Group A are 98.75% and in Group B it is 93.90%.
Bhagandara, Ashtamahagadas, Ksharasutra, Fistula-in-ano
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