In Belgium, case of new coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection from owner to domestic cat was reported on March 27, 2020. So far, cases of SARS-CoV-2 infection from owners to their dogs have been reported. For the first time in the world, the case of SARS-CoV-2 transmission from the owner to a domestic cat has been confirmed. A tiger kept at a zoo in New York, USA, was reportedly infected with SRAS-CoV-2. It is believed that SRAS-CoV-2 has been transmitted to tiger from caretakers infected with SRAS-CoV-2. Therefore, we examined the homology of whole molecule and the 5 amino acids residues; KGDFR located in the binding region of the angiotensin converting enzyme-2 (ACE2) molecule, a receptor for the spike glycoprotein on the virion surface of SRAS-CoV-2, between humans, dogs, cats, tiger and other mammals. Although the transmission of human coronavirus to pets or animals is rare, the dangers of transmitting SARS-CoV-2 from animals or pets to humans have not been proven. Our findings with Shi’s study provide important insights into the animal models for SARS-CoV-2 and animal management for COVID-19 control.
ACE2, SARS-CoV-2, COVID-19, binding region
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