Efficacy of vaccination of the COMIRNATY intramuscular injection for 5 to 11 years old (Pfizer/BioNTech) against coronavirus infectious disease-2019 (COVID-19) was high in pediatric trials conducted for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants before omicron wave. Among adults, estimated vaccine effectiveness of 2 BNT162b2 (Pfizer/BioNTech) doses against symptomatic Omicron infection was reduced compared with prior variants. It has been clarified that the incidence of side effects on BNT162b2 is higher in Japanese than in other races. Therefore, we investigated the onset of side effects on the COMIRNATY intramuscular injection for 5 to 11 years old in Japanese children (5 to 11 years old) by clinical research. From the results of clinical studies, it was clarified that the incidence of side effects on the COMIRNATY intramuscular injection for 5 to 11 years old in Japanese children is extremely low. Here, we describe the symptoms of side effects on the COMIRNATY intramuscular injection for 5 to 11 years old in Japanese children.
COMIRNATY, COVID-19, Children, side effects
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