In recent years, heavy metal pollution has become a global environmental threat both ocean and inland fresh waste eco systems. Several aquatic systems were polluted by heavy metals from the industrial discharges. The discharges not only pollute the water bodies but also the aquatic plants, animals which related to human health issues. In the present study the fish Labeo rohita was exposed to three sub-lethal concentrations of Mercuric chloride which is non-essential metal and hazardous too, representing 5, 25 and 50 % of 96 hr.LC50 respectively. The activity of antioxidant enzymes and oxidative stress due to the exposure of the heavy metal mercuric chloride induces [superoxide dismutase(SOD), catalase CAT), glutathione S.transeferase (GST)] and malondialdehyde (MDA) in the liver were investigated From the results it can be concluded that the activities and expression levels of antioxidant enzymes and oxidative stress can be used as biomarkers to evaluate the influence of heavy metal mercuric chloride as the biochemical pathway and enzymatic function in Labeo rohita that can be used for biological monitoring unacceptable levels of environmental contamination.
Mercuric chloride, Labeo rohita ,SOD, CAT, GST, LPO
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