The purpose of the study was comparative study of various parameters of marketed and formulated rifampicin tablet using castor oil. Rifampicin is used as 1st line anti-tubercular drug for the treatment of tuberculosis. Tablets were prepared by direct compression containing castor oil as a binder and various excipients. Both the marketed and prepared tablets were evaluated parameters such as Hardness, Thickness, Friability, Weight variation, Dissolution studies. The formulation of rifampicin tablet batch F1 shows optimized release of drug within 45 minutes.
Rifampicin, Ricinus Communis oil, Anti Tubercular, Tuberculosis, In-vitro Dissolution studies
International Journal of Trend in Scientific Research and Development - IJTSRD having
online ISSN 2456-6470. IJTSRD is a leading Open Access, Peer-Reviewed International
Journal which provides rapid publication of your research articles and aims to promote
the theory and practice along with knowledge sharing between researchers, developers,
engineers, students, and practitioners working in and around the world in many areas
like Sciences, Technology, Innovation, Engineering, Agriculture, Management and
many more and it is recommended by all Universities, review articles and short communications
in all subjects. IJTSRD running an International Journal who are proving quality
publication of peer reviewed and refereed international journals from diverse fields
that emphasizes new research, development and their applications. IJTSRD provides
an online access to exchange your research work, technical notes & surveying results
among professionals throughout the world in e-journals. IJTSRD is a fastest growing
and dynamic professional organization. The aim of this organization is to provide
access not only to world class research resources, but through its professionals
aim to bring in a significant transformation in the real of open access journals
and online publishing.