Thrombocytopenia is defined as a platelet count that falls below its normal range. The normal value of platelets for an adult is 150000 to 450000/ microliter. A platelet count of more than 450000/microliter is called thrombocytosis and a platelet count of less than 150000/microliter is called thrombocytopenia. Various types of thrombocytopenia occur based on theircause such as immune thrombocytopenic purpura, heparin-induced thrombocytopenia, thrombotic thrombocytopenic purpura, immune thrombocytopenia, and drug-induced thrombocytopenia. Various causes of thrombocytopenia are due to some of the drugs, diseases and disorders, chemical exposures, microorganisms, and some rare conditions that cause blood clots. The underlying pathophysiology of thrombocytopenia is decreased platelet production, increased platelet destruction, and platelets redistribution. The effective diagnosis and treatment may help the patient improve in their quality of life and help to achieve an optimal therapeutic outcome. The scope of this review is to describe thrombocytopenia, types, etiology, pathophysiology, diagnosis, pharmacological treatment, non-pharmacological treatment, and its prevention.
Thrombocytopenia, Etiology, Types, Pathophysiology, Sign and Symptoms, Diagnosis, Treatment
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