Guillain Barre Syndrome is characterized by the emergence of distal, relatively symmetrical paraesthesia. It occurs when the body's defensive mechanisms mistakenly assault parts of the neurological system. It is classified into subtypes as Acute inflammatory demyelinating polyneuropathy (AIDP),Acute motor axonal neuropathy (AMAN),Acute motor sensory axonal neuropathy (AMSAN),Pharyngeal–cervical brachial variant, and Miller Fisher syndrome.GBS can be caused by a variety of infections such as Campylobacter jejuni infection, cytomegalovirus, Epstein-Barr virus, and Human Immunodeficiency virus. It mainly causes the motor, sensory, and autonomic dysfunction. In the diagnosis of GBS, a lumbar puncture is an important diagnostic tool.Anti-GD1a is linked to the GBS subtype AMAN. Miller-Fisher syndrome is linked to anti-GQ1b.Its treatment includes, Plasma exchange, Immunoglobulin, and corticosteroids. As it is incurable, supportive care and respiratory support is recommended.
Guillain Barre Syndrome, Axonal neuropathy, Demyelination, Paraesthesia
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