The Varicella-zoster virus (VZV) or human herpes virus 3 is a neurotropic human alpha herpes virus responsible for chickenpox/varicella and shingles/Herpes zoster (HZ).HZ represents a reactivation of VZV in the host and has gained interest because of variable clinical presentation, which is important in the differential diagnosis of diseases. Furthermore, HZ complications are potentially life-threatening. HZ reactivation has been reported as a possible adverse event after COVID-19 vaccination. HZ reactivation has recently been observed after COVID-19 vaccination. The disease shows different clinical stages. A person’s immune system weakens as they age. The more the immune system weakens, the less likely it is to prevent the virus from reactivating. Hence, older people are more at risk from Shingles.The varicella zoster virus is responsible for chickenpox (also known as herpes zoster). After a person has chickenpox, the virus stays in their body and becomes inactive. The virus can become active again years later and cause Shingles. Scientists aren’t exactly sure what causes the virus to become active again. However, there may be multiple factors.
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