Seamless capsules formed of a shell material encapsulating a core material have been made by using as the shell material film-forming materials such as gelatin and gums. Seamless capsules have a clear and glossy appearance with liquid material encapsulation and show greater bioavailability and flexible adjustment of the dosage.Encapsulation refers to a variety of dosage forms used to enclose drugs in a relatively rigid shell known as a capsule, enabling them to be taken orally or as suppositories, for example, in the manufacture of pharmaceuticals.Capsules are divided into two main types: Hard-shelled capsules that contain dry, powdered ingredients or miniature pellets made by extrusion or spheronization techniques.These are made in two parts: The first half is made of aluminium.A smaller-diameter "body" that is filled and then sealed with a larger-diameter "cap" attached to a smaller-diameter "body".Soft-shelled capsules, mainly used for oils and for active ingredients that are dissolved or suspended in oil, are mainly used for oils and for active ingredients that are dissolved or suspended in oil.Seamless capsules come under the category of soft gelatin capsules. The bioavailability of these capsules is found to be more potent than other soft gelatin capsules. Some of these capsules show resistance to high temperatures whereas, some can withstand the acidic pH of the stomach, there are still some that show rapid dissolution i.e., they dissolve in the mouth itself. Due to these factors, this type of capsule can be considered superior to the rest.
Capsules, seamless, soft gelatin, bioavailability, encapsulation
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