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Preparation and Evaluation of Immediate Release Tablets

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Preparation and Evaluation of Immediate Release Tablets


Sakshi Ghuge | Prof. Smita More



Sakshi Ghuge | Prof. Smita More "Preparation and Evaluation of Immediate Release Tablets" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-5 | Issue-1, December 2020, pp.142-150, URL: https://www.ijtsrd.com/papers/ijtsrd35867.pdf

Background: Tablet is that the preferred among all dosage forms existing today thanks to its convenience of self administration, compactness and simple manufacturing; however in many cases immediate onset of action is required than conventional therapy. There are novel kinds of dosage form.The scenario of pharmaceutical drug delivery are expeditiously challenging, but conventional pharmaceutical dosage forms are still dominating. Immediate release dosage forms are those wherein =85% of labeled amount dissolves within 30 min. Superd is integrants are accustomed improve the efficacy of solid dosage forms. orms that act very quickly after administration To overcome these drawbacks, immediate release pharmaceutical dosage form has emerged as alternative oral dosage forms. There are novel forms of dosage forms that act very quickly after administration. the fundamental approach utilized in development tablets is that the use of superdisintegrants like Cross linked carboxymelhylcellulose (Croscarmeliose), Sodium starch glycolate (Primogel, Explotab), Polyvinylpyrrolidone (Polyplasdone) etc. which give instantaneous disintegration of tablet after administration. Immediate release liquid dosage forms and parenteral dosage form have also been introduced for treating patients. Dosage form can be suspensions with typical dispersion agents like hydroxypropylmethylcellulose, (dioctylsulfosuccinate) etc. a replacement dosage form allows a manufacturer to increasemarket exclusivity, while offering its patient population a more convenient dosage form or dosing regimen.These superdisintegrants provide instantaneous disintegration of the tablet after administration within the stomach. This article provide an exhaustive account illustrating the significances of superdisintegrant within the immediate release of tablets and therefore the mechanism of disintegration together with various conventional techniques and novel granulation technology wont to prepare immediate-release tablets. ach. Thus, decreasing the disintegration time which successively enhances drug dissolution rate. Results: From this review, we can ready to develop and evaluate immediate release tablets.also we must always understand role of immediate release tablets.Conclusion: Most of the patients need quick therapeutic action of the drug, leading to poor compliance with conventional drug therapy which results in reduced overall therapy effectiveness. For this we will conclude that immediate release tablets are simpler. because immediate release tablet shows quick effect.

Immediate release tablets, evaluation


IJTSRD35867
Volume-5 | Issue-1, December 2020
142-150
IJTSRD | www.ijtsrd.com | E-ISSN 2456-6470
Copyright © 2019 by author(s) and International Journal of Trend in Scientific Research and Development Journal. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (http://creativecommons.org/licenses/by/4.0)

International Journal of Trend in Scientific Research and Development - IJTSRD having online ISSN 2456-6470. IJTSRD is a leading Open Access, Peer-Reviewed International Journal which provides rapid publication of your research articles and aims to promote the theory and practice along with knowledge sharing between researchers, developers, engineers, students, and practitioners working in and around the world in many areas like Sciences, Technology, Innovation, Engineering, Agriculture, Management and many more and it is recommended by all Universities, review articles and short communications in all subjects. IJTSRD running an International Journal who are proving quality publication of peer reviewed and refereed international journals from diverse fields that emphasizes new research, development and their applications. IJTSRD provides an online access to exchange your research work, technical notes & surveying results among professionals throughout the world in e-journals. IJTSRD is a fastest growing and dynamic professional organization. The aim of this organization is to provide access not only to world class research resources, but through its professionals aim to bring in a significant transformation in the real of open access journals and online publishing.

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