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Non-drug therapy includes: [5] Attal N., Lanteri-Minet M., Laurent B. et al. (2011) The
physiotherapy - hardware procedures based on the use specific disease burden of neuropathic pain: results of
of physical factors for treatment and improvement: a French nationwide survey. Pain 152: 2836-2843.
infrared radiation, ultrasound, magnetic fields, light,
[6] Baron R., Freynhagen R., Tölle T.R. et al. (2010) The
heat, etc .;
efficacy and safety of pregabalin in the treatment of
acupuncture (acupuncture, reflexology) - the oldest
neuropathic pain associated with chronic lumbosacral
practice of point impact on the human body in order to
relieve symptoms and, ideally, eliminate the causes of radiculopathy. Pain, 150 (3): 420-427 (doi: 10.1016 /
j.pain.2010.04.013).
the disease;
massage is a gentle but highly effective health- [7] Berger A., Dukes E.M., Oster G. (2004) Clinical
improving procedure that increases muscle and skin characteristics and economic costs of patients with
tone, improves blood flow and thus helps the body to painful neuropathic disorders. J. Pain, 5: 143-149.
recover. [8]
Center for Clinical Practice at NICE (UK) (2010)
Conclusion Neuropathic pain: the pharmacological management
of neuropathic pain in adults in non-specialist
The currently available evidence of the high efficacy of
settings. London: National Institute for Health and
pregabalin for the treatment of NBS, both in monotherapy
Clinical Excellence (UK).
and in combination with other drugs, allows the use of non-
drug therapy, including for radiculopathy. The combination [9] Colloca L., Ludman T., Bouhassira D. et al. (2017)
of pregabalin with other drugs, in particular NSAIDs, Neuropathic pain. Nat. Rev. Dis. Primers, 3: 17002.
contributes to more effective relief of pain syndrome,
reduces the severity of anxiety-depressive disorders, and [10] Tesfaye S., Boulton A.J., Dickenson A.H. et al. (2013)
Mechanisms and management of diabetic painful
also improves the quality of life of patients with
distal symmetrical polyneuropathy. Diabetes Care, 36:
radiculopathy.
2456-2465.

Thus, the development of pathogenetically grounded [11] Tolle T., Dukes E., Sadosky A. et al. (2006) Patient
principles of treatment for radiculopathy is a complex burden of trigeminal neuralgia: results from a cross-
problem, the solution of which can be achieved by attracting sectional survey of health state impairment and
a wide range of specialists and an integrated approach to treatment patterns in six European countries. Pain
therapeutic measures, including not only pharmacotherapy, Pract., 6 (3): 153–160.
but also psychotherapy, as well as an orthopedic regimen. [12]
Gore M., Dukes E., Rowbotham D.J. et al. (2007)
Literature Clinical characteristics and pain management among
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[3] Kryzhanovsky G.N. (2001) Central pathophysiological the first time in routine medical practice in primary
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[4] Andre V., Rigoulot M.A., Koning E. (2003) Long-term neuropathic pain: a multicenter cohort study. Eur. J.
pregabalin treatment protects basal cortices and Pain, 17 (10): 1547-1557.
delays the occurrence of spontaneous seizures in the
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